You may find you are unable to create Auto-Layout Constraints using Ctrl+Drag. This is because Xcode does not recognize certain key combinations remotely.
However, there is a workaround.
To select multiple components to add the new constraint select one of the components on the View Controller (as seen circled in ORANGE). While holding down the SHIFT key, select the other components. With the components select go to the bottom right (as seen circled in RED).
To clear any constraints you can use the button in the bottom right that has the triangle in the center (seen circled in RED).